Cuff Inflation
Appropriate cuff inflation will 
  Prevent major pulmonary aspirations 
  Decrease the risk of inadvertent tracheal extubation 
  Provide a patent airway for ventilation and removal of secretions 
The most desirable cuff provides a maximum airway seal with minimal tracheal wall pressure. 
A high volume – low pressure cuff allows a large surface area to come into contact with the tracheal wall. Therefore, the pressure is distributed over a greater area. 
The amount of pressure and volume necessary to obtain a seal and prevent mucosal damage depends on the tube size, design, cuff configuration, mode of ventilation and patients' arterial blood pressure. 
A sphygmomanometer is a device used by respiratory therapy to evaluate the amount of cuff pressure. 
Routine cuff deflation is unnecessary but may be indicated to:
  Evaluate cuff leak 
  Clear upper airway secretions 
  Allow the patient to vocalize 
  After intubation, CPR or Surgery to evaluate air in cuff 
