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MEDICATION
-**How prepared |
CONCENTRATION
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Normal
dosing |
Normal
range |
Comments |
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Abciximab(Reopro) - RN |
9mg/250cc |
A. mcg/kg/MIN B. mcg/MIN |
A. AFTER
intervention =0.125mcg/kg/MIN for 12 hours to a maximum of 10 mg/min B. PRE INTERVENTION = 10 mcg/MIN |
Loading dose = 0.25mg/kg bolus Please note different doses PRE and POST intervention Monitor platelets at 2, 4 and 24 hours |
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Aminocaproic Acid(Amicar)- RN/P |
10 grams/100cc |
grams/HOUR |
1.0-3.0 grams/HOUR |
Loading dose 5 Grams over 1 hours |
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Amiodarone (Cordorone) - P |
900 mg/500cc D5W |
mg/MIN |
1.0
mg/min over 6 HOURs = 33.3cc/hr THEN 0.5 mg/MIN = 16.6 cc/HOUR |
Loading dose = 150mg/100cc D5W over |
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Aprotinin (Trasylol) - B |
1,000,000KIU/100cc 2,000,000KIU/200cc |
KIU/HOUR Or mg/HOUR |
250,000 KIU/HOUR = 35 mg/HOUR OR 500,000 KIU/HOUR = 70 mg/HOUR |
1.4mg=10,000KIU |
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Argatroban - P |
250mg/250cc NaCl |
mcg/kg/MIN |
2-10 mcg/kg/MIN |
See Argatroban protocol.
Monitor dose in liver failure |
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Ativan see Lorazapam
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Bumetanide (Bumex) - P |
10mg/100cc |
mg/HOUR |
0.5-1.0 mg/HOUR |
12 mg/day maximum |
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Cardene see Nicardipine |
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Cardizem see Diltiazem |
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Cisatricurium (Nimbex) - P
|
200mg / 100cc |
mcg/kg/MIN |
1-3 mcg/kg/MIN |
Use twitch and BIS monitor |
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Cordarone see Amiodarone |
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Corlapam see Fenoldapam |
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Dexmedetomidine(Precedex) - P |
400mcg/100cc NaCl |
mcg/kg/HOUR |
0.2-2.0 mcg/kg/HOUR |
SEE SEDATION PROTOCOL |
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Diltiazem (Cardizem) - RN/P |
125 mg/125cc: Add 125
mg/25cc to 100cc bag = 125 mg in
125cc |
mg/HOUR |
5- 15 mg/HOUR (5cc-15cc/HOUR) |
Loading dose = 0.25mg/kg (first bolus) 0.35/mg/kg (second bolus) |
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Dobutamine
(Dobutrex) - B |
500 mg/250cc |
mcg/kg/MIN |
2.0-20 mcg/kg/MIN |
Usual dose = 2.5-10mcg/kg/min |
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Drotrecogin (XIGRIS) - P
|
20 mg/100cc |
mcg/kg/HOUR |
CONSTANT RATE OF 24mcg/kg/HOUR |
PLEASE NOTE:
CONSTANT RATE = 24mcg/kg/HOUR X 96 hours. Dedicated line. Mark
start date on MAR |
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Dopamine (Intropin) - B
|
400 mg/250cc |
mcg/kg/MIN |
3-20mcg/kg/MIN |
Renal dosing = 1-5 mcg/kg/MIN |
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Doxapram - P
|
400mg/100cc |
mg/MIN |
1-3 mg/MIN |
Start at 5 mg/min then reduce to 1-3mg/min |
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Epinephrine (Adrenaline) – RN/P
|
4mg/250cc |
mcg/MIN |
1-4 mcg//MIN - vasopressor |
For treatment of asthma:
Range = 1-2 mcg/MIN |
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Epoprostenol (Flolan) - P |
500,000 nanograms/100cc |
Nanograms/kg/min |
Start at 2 nanograms/kg/MIN |
Increase
by 2 nanograms/kg/min q 15 min until |
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Eptifibatide (Integrilin) - RN |
75 mg/100cc 200 mg/100cc |
mcg/kg/MIN |
2mcg/kg/MIN for all uses For creatinine > 2 = 1 mcg/kg/MIN |
Bolus = 180 mcg/kg Maximum rate = 20 ml/hour |
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Esmolol (Brevibloc) - B |
2500 mg/250cc |
mcg/kg/MIN |
50-200 mcg/kg/MIN |
Loading
Dose = 500 mcg/kg/min over 1 minute |
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Fenoldapam (Corlapam) - P |
10 mg/250cc |
mcg/kg/MIN |
Renal perfusion = 0.03-0.05 mcg/kg/MIN |
Hypertension: 0.03-1.6 mcg/kg/MIN |
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Fentanyl
(Sublimaze) - P
|
2500 mcg/250cc |
mcg/kg/HOUR |
1-3 mcg/kg/HOUR |
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Flolan see epoprostenol |
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Furosemide (Lasix) – P |
100mg/100cc |
mg/HOUR |
5-10mg/HOUR |
After 10 mg consider adding
another diuretic |
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Heparin - B |
25000 units/500cc |
units/HOUR |
400-2000 units/HOUR (8cc-40cc/HOUR) |
See heparin protocol |
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Insulin (Regular Humulin) –P |
50 units/100cc |
units/HOUR |
0.5 – 16 units/HOUR (1cc-32 cc/HOUR) |
See insulin protocol |
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Integrillin see Eptifibatide |
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Isoproteranol (Isuprel) - P
|
1mg/250cc |
mcg/MIN |
2-20 mcg/MIN |
Bolus with 0.02-0.06 mg X 1 |
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Kphosphorous drip - P |
15mmol/250cc 30mmol/250cc |
mmol/HOUR |
Run at 50 cc/HOUR |
Run over at least 4 hours. 30 mmol= 44.4meqKCL |
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Labetolol (Trandate/Normodyne) – P |
200 mg/250cc 400 mg/250cc |
mg/MIN |
0.5-3 mg/MIN |
20 mg over 2 min |
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Lasix see furosemide |
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Lidocaine (Xylocaine) - B
|
2 grams/500cc |
mg/MIN |
1-4 mg/MIN (15cc-60cc/HOUR) |
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Lorazapam (Ativan) - P |
50 mg/100cc |
mg/HOUR |
0.5-5mg/HOUR (1cc-10cc/HOUR) |
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Magnesium Sulfate - B
|
1 Grams/100cc 4 Grams/100cc |
grams/HOUR |
1 - 2 grams over 1 HOUR |
electrolyte protocol suggested |
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Midazolam (Versed) - P |
50 mg/100cc |
mg/HOUR |
0.5-6 mg/HOUR (1cc-12cc/HOUR) |
Limited to 48 hour or less of infusion |
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Milronone (Primacor) - B |
40 mg/200 cc |
mcg/kg/MIN |
0.375-0.75 mcg/kg/MIN |
Loading dose = 50 mcg/kg over 10 min |
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Nesiritide (Natrecor) – P |
1.5 mg/250cc |
mcg/kg/MIN |
0.01-0.03 mcg/kg/MIN |
Bolus dose = 2.0 mcg/kg |
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Nicardipine(Cardene)– P |
50 mg/100cc |
mg/HOUR |
5-15 mg/HOUR |
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Nitroglycerine (Tridil) - B |
50 mg/250cc |
mcg/MIN |
10 -400 mcg/MIN (3cc-72cc/HOUR) |
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Nitroprusside(Nipride)-RN |
50 mg/250cc |
mcg/kg/MIN |
0.5-10mcg/kg/MIN |
Usual dose = 3mcg/kg/min Watch for cyanide toxicity |
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Norepinephrine (Levophed) – RN/P |
4 mg/250cc D5W 8 mg/250cc D5W |
mcg/MIN |
0.5 – 30 mcg/MIN |
Mix in D5W if possible |
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Octreotide(Sandastatin)- P |
500mcg/100cc |
mcg/HOUR |
25-50 mcg/HOUR |
For variceal bleeding |
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Phenylephrine (Neosynephrine) – RN/P |
10 mg/250cc 20 mg/250cc |
mcg/MIN |
10-180 mcg/MIN |
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Primacor see Milronone |
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Procainamide(Pronestyl)– P |
2 grams/500cc |
mg/MIN |
1.0-4 mg/MIN 15-60cc/HOUR |
Bolus = load 15-17 mg/kg over at least 30 minutes. Monitor Proc/NAPA levels and QT |
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Pronestyl see Procainamide |
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Propofol - B
|
200 mg/20ml 500mg/50ml |
mcg/kg/MIN |
5-50 mcg/kg/MIN |
Change tubing every 12 hours and Document on MAR |
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Thiopental - P
|
2000mg/500cc |
mg/kg/HOUR |
6-12mg/kg/HOUR for burst suppression |
Burst
suppression should be verified by BIS/EEG |
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Urokinase - P
|
250,000units/250ccNS |
units/HOUR |
60,000-100,000units/HOUR |
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Vasopressin -
RN/P
|
100 units/500cc 20units/100cc |
units/MIN |
SEPSIS= up to 0.04 units/MIN |
For pulseless VT/VF – 40units IVPush |
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Versed see Midazolam
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Xigris see Drotrecogin
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** How prepared: B = premixed bag in pyxis RN = RN prepares drip P = Pharmacy prepares drip